{"id":48259,"date":"2024-07-20T09:52:39","date_gmt":"2024-07-20T07:52:39","guid":{"rendered":"https:\/\/lvl-technologies.com\/casestudy\/centralized-biobank-structures-in-university-hospitals\/"},"modified":"2026-04-24T09:59:56","modified_gmt":"2026-04-24T07:59:56","slug":"zentralisierte-biobankstrukturen-in-universitaetskliniken","status":"publish","type":"casestudy","link":"https:\/\/lvl.gundf-developer.de\/en\/casestudy\/zentralisierte-biobankstrukturen-in-universitaetskliniken\/","title":{"rendered":"Centralized biobank structures in university hospitals"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=&#8221;Application note &#8211; Centralized biobank structures in<br \/>\nuniversity hospitals&#8221; font_container=&#8221;tag:h1|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space height=&#8221;70px&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;61933&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading text=&#8221;High-quality biospecimens and associated<br \/>\nmedical information for modern biomedical research&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]Biospecimens hold significant value for modern biomedical research. There is consensus within the medical-scientific community that biobanks can significantly contribute to uncovering the causes, mechanisms, and influencing factors of diseases, enabling more precise and reliable diagnoses and more effective treatments. The quality of human biospecimens and their associated data is<br \/>\nof utmost importance for achieving reliable and reproducible scientific results. To ensure this, all subprocesses within biobanks, such as acquisition, processing, storage, and distribution of biospecimens, must be executed with the highest quality standards and transparently documented.<\/p>\n<p>The LVL SAFE\u00ae 2D Tubes enable verifiably secure and space-saving storage of various types of samples, as well as secure identifiability. In addition to being suitable for manual laboratory processes, the products are also excellent for automated processing and storage across all temperature ranges. They exhibit high compatibility with existing systems. An optimal workflow<br \/>\nis achieved through the use of LVL SAFE\u00ae 2D Barcode Scanners (for automated code scanning of tubes and racks) and LVL SAFE\u00ae 8-Channel and 96-Channel Cappers\/Decappers (for opening and closing the tubes). These products are used in biobanks worldwide.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;70px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading text=&#8221;Zebanc<br \/>\n\u2013 Central biobank Charit\u00e9 \u2013<br \/>\nin the largest university hospital in Europe&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]The Central Biobank Charit\u00e9 \u2013 abbreviated as ZeBanC \u2013 is a joint core facility of the Charit\u00e9 and the Berlin Institute of Health at Charit\u00e9 (BIH). It is a clinically oriented biobank for the quality-controlled storage of biospecimens derived from clinical processes. In close collaboration with clinical colleagues, ZeBanC assists in the processing and storage of biospecimens (tissues, fluids, derivatives) and provides samples for translational research projects. The biobank\u2019s quality management system is certified according to DIN EN ISO 9001:2015.<\/p>\n<p>The use of biospecimens has already contributed to new research insights in numerous studies. Selected project examples include the National Pandemic Cohort Network (NAPKON), a high-quality cohort collection of patients with the coronavirus disease; TransBioline, a European study on biomarker research; and the BeLOVE study (Berlin Long-term Observation of Vascular Events) of the BIH, a cohort study investigating cardiovascular diseases.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;61934&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;70px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;61935&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading text=&#8221;Samples &amp; Processes&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<ul>\n<li data-start=\"0\" data-end=\"77\" data-section-id=\"vtpyry\">Sample collection in the clinic after obtaining patient consent.<\/li>\n<li data-start=\"78\" data-end=\"204\" data-section-id=\"1l8gnp2\">Transfer of samples (e.g., EDTA blood, serum) along with a completed sample processing form to ZeBanC.<\/li>\n<li data-section-id=\"qzq2up\" data-start=\"205\" data-end=\"634\">Processing (e.g., centrifugation, PBMC isolation) of the sample and aliquoting into LVL SAFE\u00ae 2D Tubes, for which pre-prepared, study-specific aliquoting sets with tubes and racks are provided by ZeBanC staff; use of structured color schemes for the tube caps for clearly identifiable sample structures to simplify processes and reduce error susceptibility.<\/li>\n<li data-section-id=\"r0plqc\" data-start=\"635\" data-end=\"893\"><strong data-start=\"637\" data-end=\"681\" data-is-only-node=\"\">Storage in various storage systems:<\/strong>\n<ol data-start=\"686\" data-end=\"893\">\n<li data-section-id=\"8cmoh5\" data-start=\"686\" data-end=\"733\">automated storage system at \u201380\u00b0C OR<\/li>\n<li data-section-id=\"1yh6w2a\" data-start=\"736\" data-end=\"825\">automated storage system at \u2013160\u00b0C in the gas phase of liquid nitrogen OR<\/li>\n<li data-section-id=\"1orulk6\" data-start=\"828\" data-end=\"893\">conventional freezers or tanks (\u201320\u00b0C to \u2013160\u00b0C)<\/li>\n<\/ol>\n<\/li>\n<li data-section-id=\"1bk6jii\" data-start=\"894\" data-end=\"1058\">Documentation of the sample (unique sample ID using barcode), preanalytical parameters, and other associated data in a biobank information system.<\/li>\n<li data-section-id=\"51gndu\" data-start=\"1059\" data-end=\"1259\" data-is-last-node=\"\">All relevant information is linked to the code on the tubes in the database: patient assignment, sample type, sample quantity, collection timestamp, processing, storage time, storage location, etc.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;70px&#8221;][vc_row_inner][vc_column_inner][vc_custom_heading text=&#8221;Customer feedback on the use of products in biobanks \u2013<br \/>\nUser experience &amp; benefits&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<strong>Well-thought-out product design offers a variety of user benefits<\/strong><\/p>\n<ul>\n<li>Pseudonymization of samples, unique sample ID, and clear labeling \u2013 no self-labeled samples with patient names,<br \/>\n<strong>no risk of adhesive labels falling off.<\/strong><\/li>\n<li>Efficiency improvement through scanning of 2D codes during sample processing compared to traditional reaction<br \/>\nvessels, where manual assignment and verification were\/are necessary.<\/li>\n<li>Tubes are available in various sizes and with different cap colors, making them well-suited for different studies and<br \/>\nrequirements \u2013 th range remains clear and manageable.<\/li>\n<li>Significant space savings compared to sample systems with traditional reaction vessels in, for example, cardboard boxes.<\/li>\n<li>Time savings through use of the capper\/decapper when opening and closing an entire rack \u2013 all tubes in a rack or row are<br \/>\nautomatically opened or closed in one operation.<\/li>\n<\/ul>\n<p><strong>Compatibility with equipment throughout the entire process<\/strong><\/p>\n<ul>\n<li>Availability of technical drawings for the tubes and racks with precise dimensions is very helpful for evaluating suitability<br \/>\nfor use and estimating compatibility with, for example, automated systems.<\/li>\n<li><strong>Standard SBS formats of the tubes lead to high compatibility with other equipment<\/strong> used in the process chain; direct pipetting\/transfer into 96-well microtiter plates is possible.<\/li>\n<li>Automation-friendliness \u2013 good compatibility with automated systems in the process (e.g., pipetting robots, automated<br \/>\nstorage systems).<\/li>\n<\/ul>\n<p><strong>Reliable product and delivery quality as a prerequisite for long-term use<\/strong><\/p>\n<ul>\n<li>Accredited data on product quality provided in advance: certificates from accredited institutes on the seal integrity<br \/>\n(IATA\/CO2) and on the leachables and extractables of the tubes.<\/li>\n<li>Stable product quality of the vessels, both for immediate use and for long-term storage and subsequent use in<br \/>\nfuture studies \u2013 long-term supply capability ensured.<\/li>\n<li>Reuse of racks, purchase of bulk goods for sustainability.<\/li>\n<li>Fast and reliable delivery.<\/li>\n<li>Professional, pleasant communication, quick response time from LVL staff, short communication channels.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;70px&#8221;][vc_custom_heading text=&#8221;Referenzen &amp; Kontakt&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;61936&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<strong>Dr. Jenny Schlesinger<\/strong><br \/>\nCentral Biobank Charit\u00e9 (ZeBanC)<br \/>\nScientific coordination[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;61937&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<strong>Dr. Myriam Merz<\/strong><br \/>\nCentral Biobank Charit\u00e9 (ZeBanC)<br \/>\nScientific coordination[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;61894&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<strong>Tobias Haessner<\/strong><br \/>\nLVL technologies GmbH &amp; Co. KG<br \/>\nT +49 7951 95613-45<br \/>\nM +49 175 7283454<br \/>\n<a href=\"mailto:tobias.haessner@lvl-technologies.com\">tobias.haessner@lvl-technologies.com<\/a>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text css=&#8221;&#8221;]<strong>Webseite<br \/>\n<\/strong><a href=\"https:\/\/biobank.charite.de\/en\" target=\"_blank\" rel=\"noopener\">https:\/\/biobank.charite.de\/en<\/a>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; css=&#8221;.vc_custom_1776946203054{margin-bottom: -50px !important;background-color: #000000 !important;}&#8221;][vc_column][vc_empty_space height=&#8221;50px&#8221;][vc_custom_heading text=&#8221;Downloads&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23FFFFFF&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space height=&#8221;50px&#8221;]    <div class='download-item-wrapper'>\n        <div class='download-leftcolumn-wrapper'>\n            <div class='download-image-wrapper'>\n                <img decoding=\"async\" src=\"https:\/\/lvl.gundf-developer.de\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-20-114846.png\" \/>            <\/div>\n            <div class='download-date-title-wrapper'>\n                <div class=\"download-title\">Applictaion Note: Charit\u00e9<\/div>            <\/div>\n        <\/div>\n        <div class='download-rightcolumn-wrapper'>\n            <a href=\"https:\/\/lvl.gundf-developer.de\/wp-content\/uploads\/2024\/07\/LVL-Download-Application-Note-Charite.pdf\" download><\/a>        <\/div>\n    <\/div>\n    [\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"The Central Biobank Charit\u00e9 (ZeBanC) is a central facility working in close collaboration with Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin to collect, process, and store biological samples for medical research. Supported by&hellip;","protected":false},"featured_media":61940,"menu_order":0,"template":"","format":"standard","class_list":["post-48259","casestudy","type-casestudy","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.9 (Yoast SEO v26.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Central Biobank Charit\u00e9 (ZeBanC) \u2013 Scientific Coordination and Biospecimens for Research<\/title>\n<meta name=\"description\" content=\"Learn more about the Central Biobank Charit\u00e9 (ZeBanC), which collects, processes, and stores biospecimens to support clinical studies and scientific research projects. 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